PTSD study of combat veterans finds similar outcomes among common therapies

6 december 2018

In a study among United States combat veterans, researchers found no significant difference between two of the most common treatments for post-traumatic stress disorder (PTSD) and no benefit for combination treatment. The study results are published in the Dec. 5 online issue of JAMA*.

Current clinical practice guidelines recommend both trauma-focused psychotherapies, such as exposuretherapy, and antidepressants, known as selective serotonin reuptake inhibitors (SSRIs), as effective treatments for PTSD.

Investigators looked at how sertraline hydrochloride (commonly prescribed SSRI) plus enhanced medication management compared to prolonged exposure therapy plus placebo and the combination of prolonged exposure therapy plus sertraline and to help reduce the severity of PTSD symptoms over 24 weeks of treatment. Lees meer

Bron: MedicalXpress, 6 decemner 2018

*Efficacy of Prolonged Exposure Therapy, Sertraline Hydrochloride, and Their Combination Among Combat Veterans With Posttraumatic Stress DisorderA Randomized Clinical Trial, Sheila A. M. Rauch, H. Myra Kim, Corey Powell, et al, JAMA Psychiatry. Published online December 5, 2018. doi:10.1001/jamapsychiatry.2018.3412